If you really want to lose weight, go buy a good pair of running shoes, and run a. 48 to 72 hours (lactulose) Pin On Food And Drink A suppository will work faster, while oral stimulant laxatives can take up to eight hours to take effect. How quickly does ex lax work . Find a stimulant laxative for purchase here. The oil will soften as the lemon juice is very cleansing and good for the digestive system from time to time anyway. This type of laxative can take 6 to 12 hours to work. If you have any of these health problems: It started working in less than 10 min and i was in hades for 12 hrs. As the medication level drops the stimulant effect will diminish. They work by keeping water in the intestines, which causes movement of the intestines. Take this and depending on how backed up your system is it will work in one to six hrs. One pill works your body for about two days. I mean, it works on a completely different level than meds used in diets, so think thi...