But just because it is not working quickly does not mean it will not help you grow more eyelashes. Most patients report an increase in eyelash length at 4 weeks. Latisse Review Before After Side Effects And Price Periorbital lipodystrophy (fat loss around the eye) is a very rare, but reported side effect of bimatoprost (the active ingredient in latisse). How long does latisse take to work reddit . The reason it takes so long is that latisse encourages new eyelashes to grow between existing eyelashes. I had a lot of success a few years ago with this, there are nothing but positive reviews. 3 months later and my eyelashes are twice as long and thick. Once you begin this regimen, you must continue to apply each night for best results. Looking at the pictures the growth doesn’t look as dramatic as it does in real life (maybe it’s because i’m not wearing mascara in the pics). Used daily, it can increase the length of your eyelashes. Best bang for your buck in my opinio...